S-17092

Legal status

• US: Investigational New Drug

CAS Number

• 176797-26-5 ^N[UNII]

PubChem CID

• 9977327

ChemSpider

• 8152919 ^N

S-17092

Legal status
Legal status	US: Investigational New Drug
Identifiers
IUPAC name [(2S,3aS,7aS)-1([(R,R)-2-phenylcyclopropyl]- carbonyl)-2-([thiazolidin-3-yl]carbonyl)octahydro-1H-indole
CAS Number	176797-26-5 N[UNII]
PubChem CID	9977327
ChemSpider	8152919 N
UNII	8W5MLJ83KU
CompTox Dashboard (EPA)	DTXSID901028793
Chemical and physical data
Formula	C23H29FN2O2
Molar mass	384.495 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(N1CCCC1)[C@H]4N(C(=O)[C@H]3[C@H](c2ccc(F)cc2)C3)[C@H]5CCCC[C@H]5C4
InChI InChI=1S/C23H29FN2O2/c24-17-9-7-15(8-10-17)18-14-19(18)22(27)26-20-6-2-1-5-16(20)13-21(26)23(28)25-11-3-4-12-25/h7-10,16,18-21H,1-6,11-14H2/t16-,18-,19+,20-,21-/m0/s1 N Key:JNUXCIMICQKTPX-RQUKQETFSA-N N
NY (what is this?)  (verify)

S-17092 is a drug which acts as a selective inhibitor of the enzyme prolyl endopeptidase.^[1] This enzyme is involved in the metabolic breakdown of a number of neuropeptide neurotransmitters in the brain,^[2][3] and so inhibiting the action of the enzyme increases the activity of these neuropeptides. This produces nootropic effects which make S-17092 a promising and novel treatment for neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease.^[4][5]