SB-357134

SB-357134
Identifiers
	IUPAC name N-(2,5-Dibromo-3-fluorophenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide;
CAS Number	219963-52-7 [EPA];
PubChem CID	6918553;
IUPHAR/BPS	3235;
ChemSpider	5293750 ;
ChEMBL	ChEMBL329383 ;
CompTox Dashboard (EPA)	DTXSID301026949 ;
Chemical and physical data
Formula	C17H18Br2FN3O3S
Molar mass	523.22 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C3CNCCN3c1cc(ccc1OC)S(=O)(=O)Nc2cc(Br)cc(F)c2Br;
	InChI InChI=1S/C17H18Br2FN3O3S/c1-26-16-3-2-12(10-15(16)23-6-4-21-5-7-23)27(24,25)22-14-9-11(18)8-13(20)17(14)19/h2-3,8-10,21-22H,4-7H2,1H3 ; Key:BLWHAZZXRHTFJE-UHFFFAOYSA-N ;
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SB-357134 is a drug which is used in scientific research. It acts as a potent, selective and orally active 5-HT₆ receptor antagonist.^[1] SB-357134 and other 5-HT₆ antagonists show nootropic effects in animal studies,^[2]^[3]^[4] and have been proposed as potential novel treatments for cognitive disorders such as schizophrenia and Alzheimer's disease.

CAS Number

219963-52-7^N[EPA]

PubChem CID

6918553

IUPHAR/BPS

3235

ChemSpider

5293750^N

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SB-357134

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Identifiers

IUPAC name N-(2,5-Dibromo-3-fluorophenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide
CAS Number	219963-52-7^N[EPA]
PubChem CID	6918553
IUPHAR/BPS	3235
ChemSpider	5293750^N
ChEMBL	ChEMBL329383^N
CompTox Dashboard (EPA)	DTXSID301026949
Chemical and physical data
Formula	C₁₇H₁₈Br₂FN₃O₃S
Molar mass	523.22 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C3CNCCN3c1cc(ccc1OC)S(=O)(=O)Nc2cc(Br)cc(F)c2Br
InChI InChI=1S/C17H18Br2FN3O3S/c1-26-16-3-2-12(10-15(16)23-6-4-21-5-7-23)27(24,25)22-14-9-11(18)8-13(20)17(14)19/h2-3,8-10,21-22H,4-7H2,1H3^N Key:BLWHAZZXRHTFJE-UHFFFAOYSA-N^N
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