SBI-797812

Drug classNAMPT activator

CAS Number

• 2237268-08-3

PubChem CID

• 135222620

ChemSpider

• 78316901

SBI-797812

Clinical data
Drug class	NAMPT activator
Identifiers
IUPAC name 1-[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)phenyl]-3-(pyridin-4-ylmethyl)urea
CAS Number	2237268-08-3
PubChem CID	135222620
ChemSpider	78316901
ChEMBL	ChEMBL4846686
Chemical and physical data
Formula	C19H22N4O4S
Molar mass	402.47 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CC2CN(CC1O2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)NCC4=CC=NC=C4
InChI InChI=1S/C19H22N4O4S/c24-19(21-11-14-7-9-20-10-8-14)22-15-1-5-18(6-2-15)28(25,26)23-12-16-3-4-17(13-23)27-16/h1-2,5-10,16-17H,3-4,11-13H2,(H2,21,22,24) Key:KTSOHNHLOLGQCY-UHFFFAOYSA-N

SBI-797812, is a drug which acts as a selective activator of the enzyme nicotinamide phosphoribosyltransferase (NAMPT). It increases the rate of nicotinamide mononucleotide production by NAMPT and decreases feedback inhibition by NAD+. It has been researched for application as a potential anti-aging drug.^[1][2]