SC-4289

SC-4289 is a synthetic nonsteroidal estrogen which, along with mytatrienediol (SC-6924; Manvene, Anvene), was developed in the late 1950s as a potential treatment for atherosclerosis in men but was never marketed.^[2][3]

Other names6-[1'-Ethyl-2',2'-dimethyl-3'-hydroxy]propyl-β-naphthol-2-benzyl ether^[1]

Routes of
administrationBy mouth

Drug classNonsteroidal estrogen

CAS Number

• 96668-66-5 ^Y

Quick facts Clinical data, Other names ...

SC-4289

Clinical data
Other names	6-[1'-Ethyl-2',2'-dimethyl-3'-hydroxy]propyl-β-naphthol-2-benzyl ether[1]
Routes of administration	By mouth
Drug class	Nonsteroidal estrogen
Identifiers
IUPAC name 2,2-Dimethyl-3-(6'-benzyloxy-2'-naphthyl)pentanol[2]
CAS Number	96668-66-5 Y
PubChem CID	154132848
Chemical and physical data
Formula	C24H28O2
Molar mass	348.486 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC(C1=CC=C2C=C(OCC3=CC=CC=C3)C=CC2=C1)C(C)(C)CO
InChI InChI=1S/C24H28O2/c1-4-23(24(2,3)17-25)21-11-10-20-15-22(13-12-19(20)14-21)26-16-18-8-6-5-7-9-18/h5-15,23,25H,4,16-17H2,1-3H3 Key:FRDCVULRLQYMDS-UHFFFAOYSA-N

Close

The chemical structure of SC-4289 is the same as for methallenestril but differs in that it is the benzyl ether and not the methyl ether.

SC-4289 makes an appearance in the allenestrol patent,^[4] as well as a stand-alone compound in:^[5]