SCH-79797

SCH-79797
Identifiers
	IUPAC name N3-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine;
CAS Number	1216720-69-2;
PubChem CID	4259181;
ChemSpider	3466882;
ChEBI	CHEBI:94998;
Chemical and physical data
Formula	C23H25N5
Molar mass	371.488 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)C1=CC=C(C=C1)CN2C=CC3=C2C=CC4=C3C(=NC(=N4)NC5CC5)N;
	InChI InChI=1S/C23H25N5/c1-14(2)16-5-3-15(4-6-16)13-28-12-11-18-20(28)10-9-19-21(18)22(24)27-23(26-19)25-17-7-8-17/h3-6,9-12,14,17H,7-8,13H2,1-2H3,(H3,24,25,26,27); Key:AVXQPEKZIGPIJW-UHFFFAOYSA-N;

SCH-79797 is a drug which acts as a potent and selective antagonist of the thrombin receptor proteinase activated receptor 1 (PAR1).^[1] It has anticoagulant, anticonvulsant and antiinflammatory effects and has been researched as a treatment for heart attack and stroke, though never developed for medical use.^[2]^[3]^[4]^[5] It also shows antibiotic actions which are not shared with other PAR1 antagonists such as vorapaxar, so may be mediated through a different target than PAR1.^[6]^[7]

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Identifiers

IUPAC name N³-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine
CAS Number	1216720-69-2
PubChem CID	4259181
ChemSpider	3466882
ChEBI	CHEBI:94998
Chemical and physical data
Formula	C₂₃H₂₅N₅
Molar mass	371.488 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)C1=CC=C(C=C1)CN2C=CC3=C2C=CC4=C3C(=NC(=N4)NC5CC5)N
InChI InChI=1S/C23H25N5/c1-14(2)16-5-3-15(4-6-16)13-28-12-11-18-20(28)10-9-19-21(18)22(24)27-23(26-19)25-17-7-8-17/h3-6,9-12,14,17H,7-8,13H2,1-2H3,(H3,24,25,26,27) Key:AVXQPEKZIGPIJW-UHFFFAOYSA-N