SHPRH

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

E3 ubiquitin-protein ligase SHPRH is an enzyme that in humans is encoded by the SHPRH gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesSHPRH, bA545I5.2, SNF2 histone linker PHD RING helicase, RAD5
Quick facts Available structures, PDB ...
SHPRH
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSHPRH, bA545I5.2, SNF2 histone linker PHD RING helicase, RAD5
External IDsOMIM: 608048; MGI: 1917581; HomoloGene: 6489; GeneCards: SHPRH; OMA:SHPRH - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001042683
NM_173082
NM_001370327
NM_001370328

NM_001077707
NM_001284354
NM_172937

RefSeq (protein)

NP_001036148
NP_775105
NP_001357256
NP_001357257

NP_001071175
NP_001271283
NP_766525

Location (UCSC)Chr 6: 145.86 – 145.96 MbChr 10: 11.03 – 11.09 Mb
PubMed search[3][4]
Wikidata
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Function

SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases.[supplied by OMIM][6] SHPRH is a nucleosome-stimulated ATPase and a nucleosome-E3 ubiquitin ligase.[7]

References

Further reading

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