SIB-1757

SIB-1757
Identifiers
	IUPAC name 6-methyl-2-(phenylazo)-3-pyridinol;
CAS Number	31993-01-8 ;
PubChem CID	6849066;
ChemSpider	10654582;
CompTox Dashboard (EPA)	DTXSID00425754 ;
ECHA InfoCard	100.164.315
Chemical and physical data
Formula	C12H11N3O
Molar mass	213.240 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Oc1ccc(C)nc1\N=N\c2ccccc2;
	InChI InChI=1S/C12H11N3O/c1-9-7-8-11(16)12(13-9)15-14-10-5-3-2-4-6-10/h2-8,16H,1H3/b15-14+; Key:LOCPVWIREQIGNQ-CCEZHUSRSA-N;
	(verify)

SIB-1757 is a drug used in scientific research which was one of the first compounds developed that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR₅.^[1] It has anti-hyperalgesia effects in animals.^[2] SIB-1757 along with other mGluR₅ antagonists has been shown to have neuroprotective and hepatoprotective effects,^[3]^[4] and it is also used to study the role of the mGluR₅ receptor in brain development.^[5]

CAS Number

31993-01-8^Y

PubChem CID

6849066

ChemSpider

10654582

CompTox Dashboard (EPA)

DTXSID00425754

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SIB-1757

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Identifiers

IUPAC name 6-methyl-2-(phenylazo)-3-pyridinol
CAS Number	31993-01-8^Y
PubChem CID	6849066
ChemSpider	10654582
CompTox Dashboard (EPA)	DTXSID00425754
ECHA InfoCard	100.164.315
Chemical and physical data
Formula	C₁₂H₁₁N₃O
Molar mass	213.240 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Oc1ccc(C)nc1\N=N\c2ccccc2
InChI InChI=1S/C12H11N3O/c1-9-7-8-11(16)12(13-9)15-14-10-5-3-2-4-6-10/h2-8,16H,1H3/b15-14+ Key:LOCPVWIREQIGNQ-CCEZHUSRSA-N
(verify)