SR8278

SR8278
Identifiers
	IUPAC name ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate;
CAS Number	1254944-66-5;
PubChem CID	53393127;
ChemSpider	28189717;
CompTox Dashboard (EPA)	DTXSID80693813 ;
Chemical and physical data
Formula	C18H19NO3S2
Molar mass	361.47 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCOC(=O)C1CC2=CC=CC=C2CN1C(=O)C3=CC=C(S3)SC;
	InChI InChI=1S/C18H19NO3S2/c1-3-22-18(21)14-10-12-6-4-5-7-13(12)11-19(14)17(20)15-8-9-16(23-2)24-15/h4-9,14H,3,10-11H2,1-2H3; Key:UIEBLUZPSFAFOC-UHFFFAOYSA-N;

SR-8278 is an experimental drug that was developed as an antagonist of Rev-ErbAα.^[1] It has been used to demonstrate potential applications of Rev-ErbAα antagonists in the treatment of conditions such as Duchenne muscular dystrophy and Alzheimer's disease.^[2]^[3]

CAS Number

1254944-66-5

PubChem CID

53393127

ChemSpider

28189717

CompTox Dashboard (EPA)

DTXSID80693813

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[2]

[3]

SR8278

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References

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Identifiers

IUPAC name ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate
CAS Number	1254944-66-5
PubChem CID	53393127
ChemSpider	28189717
CompTox Dashboard (EPA)	DTXSID80693813
Chemical and physical data
Formula	C₁₈H₁₉NO₃S₂
Molar mass	361.47 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCOC(=O)C1CC2=CC=CC=C2CN1C(=O)C3=CC=C(S3)SC
InChI InChI=1S/C18H19NO3S2/c1-3-22-18(21)14-10-12-6-4-5-7-13(12)11-19(14)17(20)15-8-9-16(23-2)24-15/h4-9,14H,3,10-11H2,1-2H3 Key:UIEBLUZPSFAFOC-UHFFFAOYSA-N

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