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ST8SIA6

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 is a protein that in humans is encoded by the ST8SIA6 gene.[5]

AliasesST8SIA6, SIA8F, SIAT8F, ST8SIA-VI, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6, ST8SiaVI, SIAT8-F
End17,454,595 bp[1]
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ST8SIA6
Identifiers
AliasesST8SIA6, SIA8F, SIAT8F, ST8SIA-VI, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6, ST8SiaVI, SIAT8-F
External IDsOMIM: 610139; MGI: 2386797; GeneCards: ST8SIA6
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001004470
NM_001345961

NM_145838

RefSeq (protein)

NP_001004470
NP_001332890

NP_665837

Location (UCSC)Chr 10: 17.32 – 17.45 MbChr 2: 13.66 – 13.8 Mb
PubMed search[3][4]
Wikidata
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Function

Sialic acid is a key determinate of oligosaccharide structures involved in cell-cell communication, cell-substrate interaction, adhesion, and protein targeting. ST8SIA6 belongs to a family of sialyltransferases (EC 2.4.99.8) that synthesize sialylglycoconjugates (Takashima et al., 2002 [PubMed 11980897]).

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