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SUMO3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Small ubiquitin-related modifier 3 is a protein that in humans is encoded by the SUMO3 gene.[5][6]

AliasesSUMO3, SMT3A, SMT3H1, SUMO-3, Smt3B, small ubiquitin-like modifier 3, small ubiquitin like modifier 3
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SUMO3
Identifiers
AliasesSUMO3, SMT3A, SMT3H1, SUMO-3, Smt3B, small ubiquitin-like modifier 3, small ubiquitin like modifier 3
External IDsOMIM: 602231; MGI: 1336201; GeneCards: SUMO3
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006936
NM_001286416

NM_001301671
NM_001301672
NM_001301673
NM_019929

RefSeq (protein)

NP_001273345
NP_008867

NP_001288600
NP_001288601
NP_001288602
NP_064313

Location (UCSC)Chr 21: 44.81 – 44.82 MbChr 10: 77.44 – 77.45 Mb
PubMed search[3][4]
Wikidata
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Function

SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002).[supplied by OMIM][6]

Interactions

SUMO3 has been shown to interact with ARNTL[7] and Thymine-DNA glycosylase.[8]

References

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