SWAP70

SWAP70
Identifiers
Aliases	SWAP70, SWAP-70, HSPC321, SWAP switching B-cell complex 70kDa subunit, SWAP switching B-cell complex subunit 70, switching B-cell complex subunit switching B cell complex subunit SWAP70
External IDs	OMIM: 604762; MGI: 1298390; GeneCards: SWAP70
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DN6
Gene location (Human)
Chr.	Chromosome 11 (human)
End	9,752,993 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	109,882,713 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; amniotic fluid; ; sural nerve; ; cartilage tissue; ; visceral pleura; ; lower lobe of lung; ; parietal pleura; ; epithelium of nasopharynx; ; palpebral conjunctiva; ; tibia;
	Top expressed in
	mesenteric lymph nodes; ; decidua; ; spleen; ; right lung lobe; ; blood; ; left lung lobe; ; stroma of bone marrow; ; calvaria; ; lumbar spinal ganglion; ; femur;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; calcium ion binding; protein binding; ATP binding; cadherin binding;
Cellular component	cell projection; membrane; plasma membrane; cytoskeleton; nucleus; lamellipodium; cytoplasm;
Biological process	positive regulation of cytosolic calcium ion concentration; positive regulation of mast cell chemotaxis; negative regulation of peptidyl-serine dephosphorylation; negative regulation of actin filament depolymerization; actin filament bundle assembly; regulation of protein localization; regulation of actin polymerization or depolymerization; somatic cell DNA recombination; isotype switching; positive regulation of actin filament bundle assembly; negative regulation of cell-cell adhesion mediated by integrin;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	23075
	20947
	ENSG00000133789
	ENSMUSG00000031015
	Q9UH65
	Q6A028
	NM_001297714; NM_015055
	NM_009302
	NP_001284643; NP_055870
	NP_033328
	Wikidata
View/Edit Human	View/Edit Mouse

Switch-associated protein 70 is a protein that in humans and other mammals is encoded by the SWAP70 gene.^[5]^[6]^[7]^[8]

AliasesSWAP70, SWAP-70, HSPC321, SWAP switching B-cell complex 70kDa subunit, SWAP switching B-cell complex subunit 70, switching B-cell complex subunit switching B cell complex subunit SWAP70

External IDsOMIM: 604762; MGI: 1298390; GeneCards: SWAP70

PDBOrtholog search: PDBe RCSB

Chr.Chromosome 11 (human)^[1]

Quick facts Identifiers, Aliases ...

Close

[5]

[6]

[7]

[8]

[1]

[2]

[3]

[4]

SWAP70

References

Further reading

Related Articles

Timelines

Top Qs

Fact Checks

Related Articles

"Association of SWAP-70 with the B cell antigen receptor complex"

"Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs"

"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"

"SWAP-70 identifies a transitional subset of actin filaments in motile cells"

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"

"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes"