Maswime is an executive member of the South African Perioperative Research Group.[10] She is a member of the International Network of Obstetric Survey Systems.[6] She was a lecturer and Director of the University of the Witwatersrand Obstetrics and Gynaecology Clinical Research Division and an obstetrician at the Chris Hani Baragwanath Hospital Academic Hospital.[11] She works with women with high risk pregnancies.[12] Her research considers maternal near miss and mortality.[9][13] She found that maternal deaths from bleeding during caesarean sections have increased in South Africa.[14] She compared the preparedness of hospitals for surgical complications in caesarean sections in southern Gauteng.[13]
Maswime discovered that Africa accounts for 200,000 maternal deaths per year; which is two thirds of all maternal deaths worldwide.[7] In 2017, she was named by the Mail & Guardian as one of the Top 200 South Africans.[15][16] She has written for The Conversation about increasing the number of caesarean sections in Africa.[7][17] She won the Trailblazer and Young Achiever Award from Jacob Zuma in 2017.[18]
In 2018, she launched the South African Clinician Scientists Society, a collegial group for emerging specialists and researchers returning from training abroad that facilitates mentorship, networking, and multidisciplinary research.[19][20] She was awarded a Discovery Foundation Harvard University, Massachusetts General Hospital Fellowship in 2018.[21][22][23] Her fellowship allows her to research the causes of stillbirths in HIV-positive people.[24] The fellowship is worth R2.1 million.[24] During her postdoctoral year, Maswime found herself one of only two people at meetings at the World Health Organization or UNICEF.[2] She also worked on her approach to mental health as it relates to mothers and children. She has two children, Taurai (13), Farai (10).
In 2019 she was appointed as a Professor of Global Surgery at the University of Cape Town.[1] In 2020, she was announced as one of the World Economic Forum's Class of 2020 Young Scientists, a group of 25 notable researchers who are "at the forefront of scientific discovery."[25]