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Salsolidine

Chemical compound From Wikipedia, the free encyclopedia

Salsolidine, also known as 6,7-dimethylsalsolinol, O-methylsalsoline, or norcarnegine, is a tetrahydroisoquinoline alkaloid found in various cactus species.[1][2] It is pharmacologically active.[1] Salsolidine has been found to act as a weak but relatively potent monoamine oxidase inhibitor (MAOI), specifically of monoamine oxidase A (MAO-A) ((R)-enantiomer Ki = 6 μM), among other actions.[1][3]

Quick facts Names, Identifiers ...
Salsolidine
Names
IUPAC name
6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
Other names
1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methyl-isoquinoline; DMMH-4; 6,7-Dimethylsalsolinol; O-Methylsalsoline; Norcarnegine
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
EC Number
  • 837-124-7
  • InChI=1S/C12H17NO2/c1-8-10-7-12(15-3)11(14-2)6-9(10)4-5-13-8/h6-8,13H,4-5H2,1-3H3
    Key: HMYJLVDKPJHJCF-UHFFFAOYSA-N
  • COc1cc2C(C)NCCc2cc1OC
Properties
C12H17NO2
Molar mass 207.273 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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