Santa Maria do Boiaçu is an isolated village along the Branco River. Except for Santa Maria and a few riverside settlements, the region is uninhabited.[4] In 2018, the Baixo Rio Branco-Jauaperi Extractive Reserve was created which aims to protect the area while allowing for sustainable economic activities for the communities along the river.[5] Between 1960 and 1982, it was a district [pt] of Caracaraí,[6] but has become part of the municipality of Rorainópolis.[7]
Santa Maria do Boiaçu has an airfield, an elementary school, the only high school in the region, and is connected to the telephone network and internet. The village has a medical post was which renovated in 2017.[7]
The 2019 cutbacks and restructuring of FUNAI, the organisation in charge of the indigenous territories, by Jair Bolsonaro[9] has resulted in Yanomami Amerindians leaving their territory and building camps in the vicinity of the village.[3]
The BR-431 [pt] highway was supposed to connect Santa Maria do Boiaçu with the road network of Roraima, however as of 2020 only 45.6 kilometres of the planned 125 kilometres have been constructed.[10]