Anders Swenson reviewed Sea of Mystery for Different Worlds magazine and stated that "I liked this adventure. Actually, I like the solo adventures that Flying Buffalo publishes generally, and this booklet is of similar quality to the other adventures in the line. Specifically, though, it provides a relatively low-key interlude between adventures which are a bit deadlier. This solo adventure features color and playability over danger and gross rewards. It is a good buy, especially when you consider the price."[2]
Russ Williams reviewed Sea of Mystery in The Space Gamer No. 49.[1] Williams commented that "The situations are quite varied. I found one or two a bit hard to swallow, and some seemed contrived. However, it is basically a good, solid adventure with a welcome change in format from most other Flying Buffalo solo dungeons. I recommend it."[1]