Secologanin synthase
Type of enzyme
From Wikipedia, the free encyclopedia
Secologanin synthase (EC 1.14.19.62, was wrongly classified as EC 1.3.3.9 in the past) is an enzyme that catalyzes the chemical reaction
| Secologanin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.19.62 | ||||||||
| CAS no. | 258339-71-8 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The three substrates of this enzyme are loganin, reduced nicotinamide adenine dinucleotide phosphate (NADPH), and oxygen. Its products are secologanin, oxidised NADP+, and water.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with oxygen as acceptor. The systematic name of this enzyme class is loganin:oxygen oxidoreductase (ring-cleaving). It is a member of the cytochrome P450 protein superfamily and participates in indole and ipecac alkaloid biosynthesis.[3][4]
