Qambrani played several matches for the Pakistan Under-19 team in 1996 and 1997, opening the batting against the Under-19 teams of West Indies, England and South Africa.[1]
He made his first-class debut in 1998-99 for Hyderabad in the Quaid-e-Azam Trophy. In his sixth match, a few days after turning 21, he captained the team for the first time, scored his first century, and led Hyderabad to their first victory of the season by one wicket.[2]
In 2001-02 Qambrani captained Dadu to second place in the sub-first-class Grade II division of the Quaid-e-Azam Trophy. He was the most successful batsman in the tournament.[3] When Dadu were promoted to first-class status for the 2002-03 season, he retained the captaincy, and led the team's batting with 257 runs at 25.70, but Dadu won no matches and lost their first-class status after the season. They won one match in the one-day tournament, in which Qambrani scored 112 not out in a 10-run victory over Lahore Blues and shared the Man of the match award.[4]
Qambrani had his most prolific season in 2006-07 when he scored 686 runs at an average of 32.66,[5] playing for Pakistan Customs, Hyderabad and Sindh. His highest score was 150 not out, scored for Hyderabad against Islamabad in 2009-10.[6] It was the last of his eight first-class centuries. He last played first-class and List A cricket in 2011-12.