Sicótico made its debut on April 24, 2007, in the third race at a distance of 1,000 meters. Sicótico, was a super-heavy favorite at odds of 1/9, however, Sicótico failed to even complete the race as he stumbled out of the gate and unseated his rider. His first career victory would happen on July 21, 2007, in a maiden race at a distance of 1,000 meters setting a time of 1:00 2/5. Quickly after this victory, Sicótico would begin to show off his dominance at stakes level taking the Copa Simon A. Pemberton and then the La Copa El Incorruptible at 1,400 meters. This showed that Sicótico was going to be a colt that the more distance they gave him, the more he ran. He would continue racking up wins at the age of 2 managing 7 by the end of the year from distances of 1,000–1,700 meters. His seventh and final win of the year was by far one of the most visually impressive despite there being 4 other challengers 3 of them barely made it to the final turn by the time he hit the finish line shattering the track record with a time of 1:22 1/5.
If his performances at the age of 2 were anything to go on, Sicótico was going to be a monster. He made his seasonal debut La Copa Día de Duarte where he set another track record running the race in 1:44 3/5. He would go on to win 2 more races to extend his winning streak to 10 straight races in preparation for the first jewel of the Dominican Republican Triple Crown the Clásico Matías Ramón Mella. It was no challenge at all as the triple crown turned out to be nothing but a cakewalk winning the races by huge margins and not letting anyone get near him. Following his win in the triple crown, he would manage 2 more wins increasing his win streak to 16 straight before going to the biggest test of his career the Clásico del Caribe. In over 42 runnings of the race and even hosting the race in 1995 the Dominican Republic had never won it. But now was the best shot they had ever had. Sicótico did not take the lead, as jockey Joel Rosario positioned him fifth passing the post of the final 900 meters and wasn't fazed when Defensora and Venezuelan Rey Angelo passed inside. Sicótico entered third behind Defensora and the Mexican Antares. Defensora began to fade in the final meters and Sicótico took advantage of this and zoomed on by winning the race by 1 length. He had completed the course in 1:52.54 for the 1,800 meters. The Dominican Republic had gotten there first ever Clásico del Caribe there was no doubt about it now Sicótico was the best 3-year-old in the Caribbean.
He would return to the Dominican Republic where he would continue to show off his near invincibility by setting a track record for 6 furlongs with a 1:09 1/5. He then went on to get repeat wins in the Clásico Restauración and the Clásico Presidente Constitucional. He then set a second track record that year at 1 3⁄16 miles with a 1:56 1/5. By the end of his campaign in the Dominican Republic, he had stretched his winning streak to 24 straight victories. Which to this day is the 11th greatest winning streak in the history of horse racing and is tied for the third greatest winning streak of the 21st century with New Caledonia's Ivor Hill only beaten by Winx and Black Cavier. He would make his final career start in the Copa Confraternidad del Caribe a race the Dominican Republic had only won once in 1995. Arrangements were made for Joel Rosario to ride Sicótico again but commitments that were presented to him could not be specified. The decision was made for the Puerto Rican rider Jesús Manuel Ríos to be his rider in the 10 furlong race. Sicótico would play the role of stalker staying in third turning for the home stretch he could only get a slim lead as Soy Conquistador outfought him in the stretch and opened up a lead while Sicótico simply didn't have anything left fading to fifth for what would be his final start.[2]