SroB RNA
From Wikipedia, the free encyclopedia
| sroB RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of sroB | |
| Identifiers | |
| Symbol | sroB |
| Rfam | RF00368 |
| Other data | |
| RNA type | Gene; sRNA |
| Domain | Bacteria |
| SO | SO:0000655 |
| PDB structures | PDBe |
The sroB RNA (also known as MicM, rybC, or ChiX) is a non-coding RNA gene of 90 nucleotides in length. sroB is found in several Enterobacterial species, but its function is unknown.[1][2] SroB is found in the intergenic region on the opposite strand to the ybaK and ybaP genes.[1] SroB is expressed in stationary phase.[1] Experiments have shown that SroB is a Hfq binding sRNA.[2][3]
Further evidence has shown that SroB negatively regulates the outer membrane protein YbfM by sequestering the ribosome binding site of ybfM mRNA by an antisense interaction.[4] SroB also regulates the DpiA/DpiB two-component system.[5] Furthermore, SroB itself appears to be the target of a non-coding transcript from the chbBC intergenic region.[6][7][8]
