Staden Package

DNA sequence assembly software From Wikipedia, the free encyclopedia

The Staden Package is computer software, a set of tools for DNA sequence assembly, editing, and sequence analysis. It is open-source software, released under a BSD 3-clause license.

Original authorRodger Staden
DevelopersJames Bonfield, et al.
Initial release1977; 49 years ago (1977)
Stable release
2.0.0b9 / 24 January 2012; 14 years ago (2012-01-24)
Quick facts Original author, Developers ...
Staden Package
Original authorRodger Staden
DevelopersJames Bonfield, et al.
Initial release1977; 49 years ago (1977)
Stable release
2.0.0b9 / 24 January 2012; 14 years ago (2012-01-24)
Preview release
2.0.0b11 / 25 April 2016; 9 years ago (2016-04-25)
Written inC, C++, Fortran, Tcl
Operating systemUnix, Linux, macOS, Windows
PlatformIA-32, x86-64
Available inEnglish
TypeBioinformatics
LicenseBSD 3-clause
Websitestaden.sourceforge.net
Repositorysourceforge.net/projects/staden
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Package components

The Staden package consists of several different programs. The main components are:

  • pregap4 – base calling with Phred, end clipping, and vector trimming
  • trev – trace viewing and editing
  • gap4 – sequence assembly, contig editing, and finishing
  • gap5 – assembly visualising, editing, and finishing of NGS data[1]
  • Spin – DNA and protein sequence analysis

History

The Staden Package was developed by Rodger Staden's group at the Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, England, since 1977.[2][3][4] The package was available free to academic users, with 2,500 licenses issued in 2003 and an estimated 10,000 users, when funding for further development ended.[5] The package was converted to open-source in 2004, and several new versions have been released since.

During the years of active development, the Staden group published a number of widely used file formats and ideas, including the SCF file format,[6] the use of sequence quality scores to generate accurate consensus sequences,[7] and the ZTR file format.[8]

See also

References

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