Sulazepam

Chemical compound From Wikipedia, the free encyclopedia

Sulazepam is a benzodiazepine derivative. It is the thioamide derivative of diazepam. It is metabolised into diazepam, desmethyldiazepam and oxydiazepam[citation needed]. It has sedative, muscle relaxant, hypnotic, anticonvulsant and anxiolytic properties like those of other benzodiazepines.[1][2] It was never marketed.

ATC code
  • none
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Sulazepam
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • 7-Chloro-1-methyl-5-phenyl-1,3-dihydro- 2H-1,4-benzodiazepine-2-thione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H13ClN2S
Molar mass300.80 g·mol−1
3D model (JSmol)
  • ClC1=CC=C(N(C)C(CN=C2C3=CC=CC=C3)=S)C2=C1
  • InChI=1S/C16H13ClN2S/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 checkY
  • Key:MWGWTOPCKLQYEU-UHFFFAOYSA-N checkY
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Synthesis

Sulazepam synthesis:[3] U.S. patent 3,141,890

Treatment of diazepam with phosphorus pentasulfide produces the corresponding thionamide, sulazepam.

See also

References

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