Super Conserved Receptor Expressed in Brain

G protein-coupled receptor 85
G protein-coupled receptor 85
Identifiers
Symbol	GPR85
Alt. symbols	SREB2
NCBI gene	54329
HGNC	4536
OMIM	605188
RefSeq	NM_018970
UniProt	P60893
Other data
Locus	Chr. 7 q31
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Search for
Structures	Swiss-model
Domains	InterPro

G protein-coupled receptor 27
G protein-coupled receptor 27
Identifiers
Symbol	GPR27
Alt. symbols	SREB1
NCBI gene	2850
HGNC	4482
OMIM	605187
RefSeq	NM_018971
UniProt	Q9NS67
Other data
Locus	Chr. 3 p21-p14
Structures
Search for
Structures	Swiss-model
Domains	InterPro

The Super Conserved Receptor Expressed in Brain (SREB) family are a group of related G-protein coupled receptors.^[1] Since no endogenous ligands have yet been identified for these receptors, they are classified as orphan receptors. Receptors within the group include SREB1 (GPR27), SREB2 (GPR85), and SREB3 (GPR173).^[2]