Synergin gamma

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Synergin gamma also known as AP1 subunit gamma-binding protein 1 (AP1GBP1) is a protein that in humans is encoded by the SYNRG gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesSYNRG, AP1GBP1, SYNG, synergin, gamma, synergin gamma
Quick facts SYNRG, Available structures ...
SYNRG
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSYNRG, AP1GBP1, SYNG, synergin, gamma, synergin gamma
External IDsOMIM: 607291; MGI: 1354742; HomoloGene: 105680; GeneCards: SYNRG; OMA:SYNRG - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001115009
NM_194341

RefSeq (protein)
Location (UCSC)Chr 17: 37.51 – 37.61 MbChr 11: 83.86 – 83.94 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene.[6]

Interactions

AP1GBP1 has been shown to interact with AP1G1[7][8] and SCAMP1.[9]

References

Further reading

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