THEMIS2

THEMIS2
Identifiers
Aliases	THEMIS2, C1orf38, ICB-1, thymocyte selection associated family member 2, ICB1, Chromosome 1 open reading frame 38
External IDs	OMIM: 617856; MGI: 2446213; GeneCards: THEMIS2
Gene location (Human)
Chr.	Chromosome 1 (human)
End	27,886,685 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	132,523,698 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; blood; ; spleen; ; bone marrow cell; ; right lung; ; upper lobe of left lung; ; appendix; ; C1 segment; ; gallbladder;
	Top expressed in
	granulocyte; ; lymph node; ; spleen; ; mesenteric lymph nodes; ; blood; ; stroma of bone marrow; ; gastrula; ; subcutaneous adipose tissue; ; submandibular gland; ; tibiofemoral joint;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	nucleus; cytoplasm;
Biological process	inflammatory response; immune system process; cell adhesion; T cell receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	9473
	230787
	ENSG00000130775
	ENSMUSG00000037731
	Q5TEJ8
	Q91YX0
	NM_001039477; NM_001105556; NM_001286113; NM_001286115; NM_004848
	NM_001033308
	NP_001034566; NP_001099026; NP_001273042; NP_001273044; NP_004839
	NP_001028480
	Wikidata
View/Edit Human	View/Edit Mouse

Thymocyte selection associated family member 2 is a protein that in humans is encoded by the THEMIS2 gene.^[5] The gene is also known as ICB-1 and C1orf38 in humans, and the orthologue in mice is BC013712.^[5] C1orf38 has been associated with cancer susceptibility.^[6]