THOP1

THOP1
Identifiers
Aliases	THOP1, EP24.15, MEPD_HUMAN, MP78, TOP, thimet oligopeptidase 1
External IDs	OMIM: 601117; MGI: 1354165; GeneCards: THOP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1S4B, 2O36
Enzyme activity
Gene location (Human)
Chr.	Chromosome 19 (human)
End	2,815,807 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	80,918,393 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; right hemisphere of cerebellum; ; right frontal lobe; ; ventricular zone; ; right lobe of liver; ; apex of heart; ; anterior pituitary; ; muscle of thigh; ; mucosa of transverse colon;
	Top expressed in
	spermatid; ; spermatocyte; ; esophagus; ; seminiferous tubule; ; lip; ; epiblast; ; tail of embryo; ; internal carotid artery; ; embryo; ; genital tubercle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptide binding; peptidase activity; hydrolase activity; metallopeptidase activity; metal ion binding; metalloendopeptidase activity;
Cellular component	cytoplasm; mitochondrial intermembrane space; cytosol;
Biological process	proteolysis; peptide metabolic process; protein polyubiquitination;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	7064
	50492
	ENSG00000172009
	ENSMUSG00000004929
	P52888
	Q8C1A5
	NM_003249
	NM_022653
	NP_003240
	NP_073144
	Wikidata
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