TIMM23

TIMM23
Identifiers
Aliases	TIMM23, TIM23, translocase of inner mitochondrial membrane 23
External IDs	OMIM: 605034; MGI: 1858317; GeneCards: TIMM23
Gene location (Human)
Chr.	Chromosome 10 (human)
End	46,003,742 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	31,923,855 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; Brodmann area 23; ; sperm; ; biceps brachii; ; right ventricle; ; Skeletal muscle tissue of biceps brachii; ; endothelial cell; ; secondary oocyte; ; vastus lateralis muscle; ; middle temporal gyrus;
	Top expressed in
	morula; ; skeletal muscle tissue; ; quadriceps femoris muscle; ; yolk sac; ; blastocyst; ; muscle of thigh; ; heart; ; embryo; ; epiblast; ; right kidney;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; protein-transporting ATPase activity; protein transmembrane transporter activity;
Cellular component	mitochondrial inner membrane; integral component of membrane; mitochondrial intermembrane space; TIM23 mitochondrial import inner membrane translocase complex; mitochondrion; integral component of mitochondrial inner membrane; membrane;
Biological process	protein transport; protein targeting to mitochondrion; protein import into mitochondrial matrix; intracellular protein transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	100287932
	53600
	ENSG00000265354
	ENSMUSG00000013701
	O14925
	Q9WTQ8
	NM_006327
	NM_016897
	NP_006318
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial import inner membrane translocase subunit Tim23 is an enzyme that in humans is encoded by the TIMM23 gene.^[5]^[6] This protein is part of the translocase of the inner membrane (TIM23) complex, which is involved in transporting protein across the inner mitochondrial membrane.^[7] In humans, the gene lies about 4 Mbp away from a poorly understood paralog called TIMM23B.^[8]