TLR4-IN-C34

CAS Number

• 40592-88-9

PubChem CID

• 91691128

ChemSpider

• 34500445

ChEMBL

• ChEMBL4303607

TLR4-IN-C34

Identifiers
IUPAC name [(2R,3S,4R,5R,6S)-5-acetamido-3,4-diacetyloxy-6-propan-2-yloxyoxan-2-yl]methyl acetate
CAS Number	40592-88-9
PubChem CID	91691128
ChemSpider	34500445
ChEMBL	ChEMBL4303607
CompTox Dashboard (EPA)	DTXSID001336698
Chemical and physical data
Formula	C17H27NO9
Molar mass	389.401 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COC(=O)C)OC(=O)C)OC(=O)C)NC(=O)C
InChI InChI=1S/C17H27NO9/c1-8(2)24-17-14(18-9(3)19)16(26-12(6)22)15(25-11(5)21)13(27-17)7-23-10(4)20/h8,13-17H,7H2,1-6H3,(H,18,19)/t13-,14-,15-,16-,17+/m1/s1 Key:KMIQMFHPUJUDMC-HHARLNAUSA-N

TLR4-IN-C34 (or C34) is a drug which acts as a potent and selective antagonist of Toll-like receptor 4 (TLR4). In animal studies it blocks TLR4-mediated cytokine release and has antiinflammatory effects.^{[1][2][3][4][5]}