TNFAIP8

TNFAIP8
Identifiers
Aliases	TNFAIP8, GG2-1, MDC-3.13, NDED, SCC-S2, SCCS2, TNF alpha induced protein 8
External IDs	OMIM: 612111; MGI: 2147191; HomoloGene: 8649; GeneCards: TNFAIP8; OMA:TNFAIP8 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	119,399,688 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	50,240,240 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; epithelium of nasopharynx; ; appendix; ; bone marrow; ; white blood cell; ; mononuclear cell; ; monocyte; ; lymph node; ; bone marrow cell; ; trabecular bone;
	Top expressed in
	gastrula; ; right kidney; ; granulocyte; ; decidua; ; thymus; ; human kidney; ; primary oocyte; ; spleen; ; conjunctival fornix; ; myocardium of ventricle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein binding;
Cellular component	cytoplasm; nucleoplasm;
Biological process	negative regulation of apoptotic process; apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of apoptotic process; regulation of apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	25816
	106869
	ENSG00000145779
	ENSMUSG00000062210
	O95379
	Q921Z5
NM_014350; NM_001077654; NM_001286813; NM_001286814; NM_001286815;
	NM_001286817
	NM_001177759; NM_001177760; NM_134131; NM_001360935
NP_001071122; NP_001273742; NP_001273743; NP_001273744; NP_001273746;
	NP_055165
	NP_001171230; NP_001171231; NP_598892; NP_001347864
	Wikidata
View/Edit Human	View/Edit Mouse

Tumor necrosis factor, alpha-induced protein 8 is a protein that in humans is encoded by the TNFAIP8 gene.^[5]^[6]^[7] It is preferentially expressed in human immune cell types.^[8]