TOMSO
Pharmaceutical compound
From Wikipedia, the free encyclopedia
TOMSO, or 5-TOMSO, also known as 2-methoxy-4-methyl-5-methylsulfinylamphetamine, is a psychedelic drug of the phenethylamine and amphetamine families related to the DOx series.[1][2] It is the analogue of DOM in which the methoxy group at the 5 position has been replaced with a sulfur-containing methylsulfinyl group.[1][2]
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| Other names | 5-TOMSO; 5-TOM-sulfoxide; 2-Methoxy-4-methyl-5-methylsulfinylamphetamine |
| Routes of administration | Oral[1] |
| Drug class | Serotonergic psychedelic; Hallucinogen |
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| Duration of action | 10–16 hours[1] |
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| Formula | C12H19NO2S |
| Molar mass | 241.35 g·mol−1 |
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In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists TOMSO's dose as >150 mg orally alone or 100 to 150 mg orally in combination with alcohol and its duration as 10 to 16 hours.[1] TOMSO was reported to produce no or only threshold effects by itself at the assessed doses, but when alcohol was concomitantly ingested, clear hallucinogenic effects occurred.[1] These effects included facial distortion and remarkable time dilation, among others.[1] When combined with alcohol, "plus-two" and "plus-three" experiences occurred on the Shulgin Rating Scale.[1]
The chemical synthesis of TOMSO has been described.[1]
TOMSO was first described in the scientific literature by Alexander Shulgin and Peyton Jacob III in 1983.[2] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1]