TSSC1
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Protein TSSC1 is a protein that in humans is encoded by the TSSC1 gene.[5][6][7]
AliasesEIPR1, TSSC1, tumor suppressing subtransferable candidate 1, EIPR-1, EARP complex and GARP complex interacting protein 1
External IDsOMIM: 608998; MGI: 1289332; HomoloGene: 2481; GeneCards: EIPR1; OMA:EIPR1 - orthologs
| EIPR1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | EIPR1, TSSC1, tumor suppressing subtransferable candidate 1, EIPR-1, EARP complex and GARP complex interacting protein 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 608998; MGI: 1289332; HomoloGene: 2481; GeneCards: EIPR1; OMA:EIPR1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
This gene has been reported[8] as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene may reside on chromosome 2 rather than chromosome 11.[7]
