TUBG1

TUBG1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Z5V, 1Z5W, 3CB2
Identifiers
Aliases	TUBG1, CDCBM4, GCP-1, TUBG, TUBGCP1, tubulin gamma 1
External IDs	OMIM: 191135; MGI: 101834; HomoloGene: 833; GeneCards: TUBG1; OMA:TUBG1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	42,615,238 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	101,017,245 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; oocyte; ; gonad; ; gastrocnemius muscle; ; stromal cell of endometrium; ; trabecular bone; ; left ventricle; ; muscle of thigh; ; prefrontal cortex;
	Top expressed in
	tail of embryo; ; abdominal wall; ; perirhinal cortex; ; entorhinal cortex; ; otic vesicle; ; yolk sac; ; genital tubercle; ; internal carotid artery; ; CA3 field; ; morula;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; structural constituent of cytoskeleton; protein binding; GTPase activity; identical protein binding;
Cellular component	cytoplasm; ciliary basal body; recycling endosome; cytosol; centrosome; pericentriolar material; apical part of cell; gamma-tubulin complex; cilium; microtubule organizing center; condensed nuclear chromosome; spindle microtubule; polar microtubule; cell leading edge; centriole; cytoplasmic microtubule; microtubule; cytoskeleton; non-motile cilium; nucleus; spindle;
Biological process	meiotic spindle organization; G2/M transition of mitotic cell cycle; cytoplasmic microtubule organization; microtubule-based process; microtubule cytoskeleton organization; microtubule nucleation; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle; mitotic sister chromatid segregation; mitotic cell cycle; mitotic spindle organization;
	Sources:Amigo / QuickGO
Orthologs
	7283
	103733
	ENSG00000131462
	ENSMUSG00000035198
	P23258
	P83887
	NM_001070
	NM_134024
	NP_001061
	NP_598785
	Wikidata
View/Edit Human	View/Edit Mouse

Tubulin, gamma 1 is a protein in humans that is encoded by the TUBG1 gene.^[5] This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle.