Tachystatin
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| Tachystatin_A | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifiers | |||||||||
| Symbol | Tachystatin_A | ||||||||
| Pfam | PF11406 | ||||||||
| InterPro | IPR022717 | ||||||||
| OPM superfamily | 112 | ||||||||
| OPM protein | 2dcv | ||||||||
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| Tachystatin_B | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Tachystatin_B | ||||||||
| Pfam | PF11478 | ||||||||
| Pfam clan | CL0083 | ||||||||
| InterPro | IPR020957 | ||||||||
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Tachystatins are antimicrobial chitin-binding peptides from Japanese horseshoe crab. Amino acid residues Tyr(14) and Arg(17) in Tachystatin B are thought to be the essential residues for chitin binding.[2] These small proteins contain a cysteine-stabilised triple-stranded beta-sheet with an inhibitor cystine knot motif and show features common to membrane-interactive peptides. Tachystatin A is thought to have an antimicrobial activity similar to defensins.[1]