Taminadenant

Taminadenant
Identifiers
	IUPAC name 5-bromo-2,6-di(pyrazol-1-yl)pyrimidin-4-amine;
CAS Number	1337962-47-6;
PubChem CID	53466958;
DrugBank	DB18811;
ChemSpider	58810193;
UNII	84I5UEP321;
ChEMBL	ChEMBL3694769;
Chemical and physical data
Formula	C10H8BrN7
Molar mass	306.127 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1=CN(N=C1)C2=NC(=NC(=C2Br)N)N3C=CC=N3;
	InChI InChI=1S/C10H8BrN7/c11-7-8(12)15-10(18-6-2-4-14-18)16-9(7)17-5-1-3-13-17/h1-6H,(H2,12,15,16); Key:ATFXVNUWQOXRRU-UHFFFAOYSA-N;

Taminadenant (PBF509) is an experimental drug which acts as a selective inhibitor of the adenosine A2A receptor. It is in clinical trials for the treatment of lung cancer, and has also shown potential for applications in the treatment of movement disorders.^[1]^[2]^[3]^[4]

Identifiers

IUPAC name 5-bromo-2,6-di(pyrazol-1-yl)pyrimidin-4-amine
CAS Number	1337962-47-6
PubChem CID	53466958
DrugBank	DB18811
ChemSpider	58810193
UNII	84I5UEP321
ChEMBL	ChEMBL3694769
Chemical and physical data
Formula	C₁₀H₈BrN₇
Molar mass	306.127 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1=CN(N=C1)C2=NC(=NC(=C2Br)N)N3C=CC=N3
InChI InChI=1S/C10H8BrN7/c11-7-8(12)15-10(18-6-2-4-14-18)16-9(7)17-5-1-3-13-17/h1-6H,(H2,12,15,16) Key:ATFXVNUWQOXRRU-UHFFFAOYSA-N

Related Articles