Tetrahydrodipicolinate N-acetyltransferase
From Wikipedia, the free encyclopedia
Tetrahydrodipicolinate N-acetyltransferase (EC 2.3.1.89) is an enzyme that catalyzes the chemical reaction
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-2,3,4,5-tetrahydrodipicolinic_acid.svg)
| Tetrahydrodipicolinate N-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.89 | ||||||||
| CAS no. | 83588-91-4 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The three substrates of this enzyme are the (S)- enantiomer of 2,3,4,5-tetrahydrodipicolinic acid, acetyl-CoA, and water. Its products are (S)-2-acetamido-6-oxopimelic acid and coenzyme A.[1]
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N2-acetyltransferase. Other names in common use include tetrahydrodipicolinate acetylase, tetrahydrodipicolinate:acetyl-CoA acetyltransferase, acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase, acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate, and 2-N-acetyltransferase.[2] This enzyme participates in lysine biosynthesis in Bacillus megaterium.[1]
