In the April 1986 edition of White Dwarf (Issue #76), Barry Bailey reviewed both The Lords of Destiny and The Iytean Menace, which had been released simultaneously, and called both of them "very accurate simulations of the kind of stories that have made Dr. Who a popular TV regular for over 20 years." Bailey confessed that The Iytean Menace was "my favourite of the two [...] attractively illustrated with period woodcuts that enhance the carefully created Victorian atmosphere." He also enjoyed the plot, which he called "challenging, but not too intricate, and manages to interweave a healthy dose of Robert Louis Stevenson into the proceedings quite adroitly." He concluded by giving it an above-average overall rating of 8 out of 10, saying, "Gamers of the Rambo 'shoot-em-up' style of role-playing would get nothing out of it - what is called for is subtlety, tact and ingenuity."[2]
The review in the November–December 1986 edition of Different Worlds (Issue #44) also covered both The Lords of Destiny and The Iytean Menace, and proposed that neither was strikingly original, commenting, "Longtime fans of the series will agree that these concepts are nothing that the series hasn't shown more than once; only the details vary from other stories (of course, this is not necessarily bad, since really original ideas are extremely rare)." However, in the case of The Iytean Menace, the reviewer pointed out problems with plot if the players do not use characters that are agents of the Celestial Intervention Agency, and suggested that "the writer should have made a passing suggestion on what the gamemaster should do." The reviewer also criticized the complete lack of maps except for a general map of Victorian London, noting the extra work this would make for the gamemaster. The review concluded by giving this book a rating of 3 out of 4, saying, "Worth buying [...] what a good Doctor Who adventure needs to succeed."[1]