Thenalidine

Thenalidine is an antihistamine with anticholinergic properties used as an antipruritic drug.^[1] It was withdrawn from the US, Canadian, and UK markets in 1963 due to a risk of neutropenia.^[2]

ATC code

• D04AA03 (WHO) R06AX03 (WHO)
  R06AX53 (WHO) (combinations)

CAS Number

• 86-12-4 ^Y

PubChem CID

• 27901

DrugBank

• DB04826 ^Y

Quick facts Clinical data, ATC code ...

Thenalidine

Clinical data
ATC code	D04AA03 (WHO) R06AX03 (WHO) R06AX53 (WHO) (combinations)
Identifiers
IUPAC name 1-Methyl-N-phenyl-N-(2-thienylmethyl)piperidin-4-amine
CAS Number	86-12-4 Y
PubChem CID	27901
DrugBank	DB04826 Y
ChemSpider	25957 N
UNII	6U94N2D00F
KEGG	D07194 Y
CompTox Dashboard (EPA)	DTXSID1048835
ECHA InfoCard	100.001.501
Chemical and physical data
Formula	C17H22N2S
Molar mass	286.44 g·mol−1
3D model (JSmol)	Interactive image
SMILES s1c(ccc1)CN(c2ccccc2)C3CCN(C)CC3
InChI InChI=1S/C17H22N2S/c1-18-11-9-16(10-12-18)19(14-17-8-5-13-20-17)15-6-3-2-4-7-15/h2-8,13,16H,9-12,14H2,1H3 N Key:KLOHYVOVXOUKQI-UHFFFAOYSA-N N
NY (what is this?)  (verify)

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