Thiamylal

Thiamylal
Clinical data
Other names	Thiamylal, Thioseconal, Surital
AHFS/Drugs.com	International Drug Names
ATCvet code	QN01AF90 (WHO) ;
Legal status
Legal status	BR: Class B1 (Psychoactive drugs); CA: Schedule IV; US: Schedule III;
Pharmacokinetic data
Metabolism	Hepatic
Elimination half-life	14.3 h (cats)
Identifiers
	IUPAC name 5-(Pentan-2-yl)-5-(prop-2-en-1-yl)-2-sulfanylidenedihydropyrimidine-4,6(1H,5H)-dione;
CAS Number	77-27-0 ;
PubChem CID	3032285;
IUPHAR/BPS	7305;
DrugBank	DB01154 ;
ChemSpider	2297298 ;
UNII	01T23W89FR;
KEGG	D06106 ;
ChEBI	CHEBI:9536 ;
ChEMBL	ChEMBL440 ;
CompTox Dashboard (EPA)	DTXSID3048441 ;
ECHA InfoCard	100.000.927
Chemical and physical data
Formula	C12H18N2O2S
Molar mass	254.35 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1NC(=S)NC(=O)C1(C(C)CCC)C\C=C;
	InChI InChI=1S/C12H18N2O2S/c1-4-6-8(3)12(7-5-2)9(15)13-11(17)14-10(12)16/h5,8H,2,4,6-7H2,1,3H3,(H2,13,14,15,16,17) ; Key:XLOMZPUITCYLMJ-UHFFFAOYSA-N ;
	(verify)

Thiamylal (Surital) is a barbiturate derivative invented in the 1950s. It has sedative, anticonvulsant, and hypnotic effects, and is used as a strong but short acting sedative. Thiamylal is still in current use, primarily for induction in surgical anaesthesia^[2] or as an anticonvulsant to counteract side effects from other anaesthetics.^[3] It is the thiobarbiturate analogue of secobarbital.