Tilapertin
Chemical compound
From Wikipedia, the free encyclopedia
Tilapertin (INN), also known as AMG-747,[1] is a investigational drug which was being evaluated as an antipsychotic.[2]
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| Formula | C20H21F3N2O2 |
| Molar mass | 378.395 g·mol−1 |
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Mechanism of action
Tilapertin appears to act via the blocking of the type 1 glycine transporter,[3] making it a glycine re-uptake inhibitor.
History
Two studies have been made in order to determine the safety of tilapertin and its potential as an add-on to anti-psychotic therapy in people with schizophrenia. These studies were later halted due to a case of Stevens–Johnson syndrome in one of the participants.[3]
