Moll was selected by the Green Bay Packers in the fifth round of the 2006 NFL draft.[4][5] Considered a "fringe" NFL draft pick, Packers coach Mike McCarthy said, "If you'd told me Tony Moll would be starting for us in the spring after the first minicamp, frankly, I would've taken that bet."[3] Even his mother, Gina Moll, noted, "When he first got drafted, we said 'OK, let's just hope he makes the practice squad.'"[3] The 6 foot, 5 inch rookie surprised McCarthy, earned a spot in the Packers' lineup, and became "a blocking mainstay" for Green Bay quarterback Brett Favre.[6] He appeared in all 16 games for the 2006 Packers, starting five games each at right guard and right tackle.[1][5] In his second season with the Packers, Moll suffered a pinched nerve in his neck during training camp.[6] He recalled, "There was a flash of pain. It resulted in pins and needles in my fingers, like when you hit your funny bone."[1] He missed the first five games of the season due to the injury, started the next three games, and then re-injured himself.[1] He appeared in a total of nine games in 2007, three as a starter.[5] As a third-year player in 2008, Moll split his playing time between the right guard and right tackle positions. He appeared in 14 games for the 2008 Packers, but only five as a starter.[5]
In September 2009, Moll was traded to the right Baltimore Ravens for defensive back Derrick Martin.[7] Moll appeared in five games for the Ravens in 2009, none as a starter.[5] In April 2010, the Ravens re-signed Moll as a restricted free agent to a one-year, $1.176 million contract.[8][9]
Moll signed with the Jacksonville Jaguars on August 10, 2011. He was released on September 3.
The San Diego Chargers signed him on November 15, 2011. He became an unrestricted free agent at the end of the 2011 season.
The Washington Redskins signed him on August 4, 2012.[10] He was released by the team on August 27.[11]