Tooth and nail syndrome
Medical condition
From Wikipedia, the free encyclopedia
Tooth and nail syndrome (also known as hypodontia with nail dysgenesis, Witkop syndrome, or mucoepithelial dysplasia syndrome)[1][2][page needed] is a rare disorder, first described in 1965, characterized by nails that are thin, small, and friable, and which may show koilonychia at birth.[2]: 521 [3] It was named after Dr. Carl J. Witkop Jr., who first described it between 1978 and 1982.[1] It is an autosomal dominant type of ectodermal dysplasia.[4] Its estimated incidence is 2 in 10,000.[4]
| Tooth and nail syndrome | |
|---|---|
| |
| This condition is inherited in an autosomal dominant manner. | |
| Specialty | Medical genetics  |