Triclofos

Triclofos (brand names Triclos, Pedicloryl) is a sedative drug used rarely for treating insomnia.^[2]

Trade namesTriclos, others

AHFS/Drugs.comInternational Drug Names

ATC code

• N05CM07 (WHO)

Legal status

• BR: Class C1 (Other controlled substances)^[1]

Quick facts Clinical data, Trade names ...

Triclofos

Clinical data
Trade names	Triclos, others
AHFS/Drugs.com	International Drug Names
ATC code	N05CM07 (WHO)
Legal status
Legal status	BR: Class C1 (Other controlled substances)[1]
Identifiers
IUPAC name 2,2,2-trichloroethanol dihydrogen phosphate
CAS Number	306-52-5 N 8060-81-9
PubChem CID	5563
ChemSpider	5362 Y
UNII	J712EO9048
KEGG	C07165
ChEMBL	ChEMBL1201317 N
CompTox Dashboard (EPA)	DTXSID9023700
ECHA InfoCard	100.005.624
Chemical and physical data
Formula	C2H4Cl3O4P
Molar mass	229.37 g·mol−1
3D model (JSmol)	Interactive image
SMILES ClC(Cl)(Cl)COP(=O)(O)O
InChI InChI=1S/C2H4Cl3O4P/c3-2(4,5)1-9-10(6,7)8/h1H2,(H2,6,7,8) Y Key:YYQRGCZGSFRBAM-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Close

Triclofos is a prodrug which is metabolised in the liver into the active drug trichloroethanol. The half-life of triclofos is fairly long and it may cause drowsiness the next day. Trichloroethanol may cause liver damage and triclofos should not be used for extended periods.

Triclofos is no longer available in the United States.^[3]