Trideca-7,9,11-trienoic acid

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Trideca-7,9,11-trienoic acid
Names
IUPAC name
(7E,9E,11E)-Trideca-7,9,11-trienoic acid
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C13H20O2/c1-2-3-4-5-6-7-8-9-10-11-12-13(14)15/h2-7H,8-12H2,1H3,(H,14,15)/b3-2+,5-4+,7-6+¨
    Key: CMKVWQNTXKWDNT-ICDJNDDTSA-N
  • C/C=C/C=C/C=C/CCCCCC(=O)O
Properties
C13H20O2
Molar mass 208.301 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Trideca-7,9,11-trienoic acid, or (7E,9E,11E)-trideca-7,9,11-trienoic acid, is an polyunsaturated fatty acid. It is present in Aethusa cynapium.[1][2][3]

Trideca-7,9,11-trienoic acid has been shown to have an antianxiety effect in Mus musculus, Rattus norvegicus, and Homo sapiens. It reduces hypolocomotion caused by anxiety, which was psychopharmacologically induced with mCPP, in Mus musculus and Rattus norvegicus. A 2 mg/kg dose of diazepam has a very similar effect to 20 mg/kg of trideca-7,9,11-trienoic acid. This may suggest that trideca-7,9,11-trienoic acid is also a GABA agonist like diazepam.[1][4][5][6]

Extraction from A. cynapium

Uses

References

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