Trifluoromethylaminoindane

5-Trifluoromethyl-2-aminoindane (TAI) is a drug of the 2-aminoindane family with putative entactogenic effects. It acts as a serotonin releasing agent (SRA). TAI is the 2-aminoindane analogue of norfenfluramine and has approximately 50% of the serotonergic neurotoxicity in comparison.^[1]

Other names5-Trifluoromethyl-2-aminoindane; TAI

Drug classSerotonin releasing agent; Entactogen

CAS Number

• 205652-95-5 ^N

PubChem CID

• 10420351

Quick facts Clinical data, Other names ...

TAI

Clinical data
Other names	5-Trifluoromethyl-2-aminoindane; TAI
Drug class	Serotonin releasing agent; Entactogen
Identifiers
IUPAC name 5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-amine
CAS Number	205652-95-5 N
PubChem CID	10420351
ChemSpider	8595781 N
UNII	TW974GB59E
CompTox Dashboard (EPA)	DTXSID401028481
Chemical and physical data
Formula	C10H10F3N
Molar mass	201.192 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1C(CC2=C1C=CC(=C2)C(F)(F)F)N
InChI InChI=1S/C10H10F3N/c11-10(12,13)8-2-1-6-4-9(14)5-7(6)3-8/h1-3,9H,4-5,14H2 N Key:UBDQCUBRYLGYCL-UHFFFAOYSA-N N
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