Trimethyllead chloride

Chemical compound From Wikipedia, the free encyclopedia

Trimethyllead chloride is an organolead compount with formula (CH3)3PbCl. It is a highly toxic colorless liquid.

Quick facts Names, Identifiers ...
Trimethyllead chloride
Trimethyllead chloride molecule
Names
IUPAC name
Chloro(trimethyl)plumbane[1]
Other names
  • Chlorotrimethylplumbane[1]
  • Chlorotrimethyllead[1]
  • Trimethylchlorolead[1]
  • Trimethylchloroplumbane[1]
  • Lead, chlorotrimethyl-[1]
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.014.716 Edit this at Wikidata
EC Number
  • 216-187-9
  • InChI=1S/3CH3.ClH.Pb/h3*1H3;1H;/q;;;;+1/p-1
    Key: HPQRSQFZILKRDH-UHFFFAOYSA-M
  • Cl[Pb](C)(C)C
Properties
(CH3)3PbCl
Molar mass 287.8 g·mol−1
Appearance Colorless liquid[2]
Limited[2]
Solubility Highly soluble in organic solvents[2]
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Highly toxic
GHS labelling:
GHS06: ToxicGHS08: Health hazardGHS09: Environmental hazard
Danger
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Synthesis

Trimethyllead chloride can be synthesized by reacting tetramethyllead with hydrogen chloride.[3]

Pb(CH3)4 + HCl → (CH3)3PbCl + CH4

Uses

Trimethyllead chloride is primarily used in organic synthesis and as a reagent in various chemical reactions, particularly in the preparation of organolead compounds.[2]

Biochemistry

Trimethyllead chloride inhibits δ‐aminolevulinic acid dehydratase (ALAD) in vitro, although to a lesser extent than triethyllead chloride.[4]

Reactions

Trimethyllead chloride reacts with hexamethyldilead to yield tetramethyllead and lead(II) chloride.[5]

Hazards

As typical of organolead compounds, trimethyllead chloride is a poison. It is highly toxic to the environment, with long-lasting effects.[2]

References

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