Triphenyliodoethylene

Chemical compound From Wikipedia, the free encyclopedia

Triphenyliodoethylene (TPIE), also known as iodotriphenylethylene or as phenylstilbene iodide, as well as triphenylvinyl iodide, is a synthetic nonsteroidal estrogen of the triphenylethylene group that is related to triphenylchloroethylene and triphenylbromoethylene and was never marketed.[1][2][3]

Other namesTPIE; Iodotriphenylethylene; Phenylstilbene iodide; Triphenylvinyl iodide
CAS Number
Quick facts Clinical data, Other names ...
Triphenyliodoethylene
Clinical data
Other namesTPIE; Iodotriphenylethylene; Phenylstilbene iodide; Triphenylvinyl iodide
Drug classNonsteroidal estrogen
Identifiers
  • (1-iodo-2,2-diphenylethenyl)benzene
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H15I
Molar mass382.244 g·mol−1
3D model (JSmol)
  • C1=CC=C(C=C1)C(=C(C2=CC=CC=C2)I)C3=CC=CC=C3
  • InChI=1S/C20H15I/c21-20(18-14-8-3-9-15-18)19(16-10-4-1-5-11-16)17-12-6-2-7-13-17/h1-15H
  • Key:DVJCEGLTPUEWNX-UHFFFAOYSA-N
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Although the effect of vinylic halogenation has already been discussed, it was discovered that Triphenylacrylonitrile [6304-33-2] also potently modulates the estrogen receptor.[4][5] The synthesis of this agent is described in the pendant literature.[6]

See also

References

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