Trypanocidal agent
From Wikipedia, the free encyclopedia
A trypanocidal agent is an antiprotozoal agent that acts upon trypanosome parasites.[1]
Examples include:[2]
Resistance
As of 2008[update], 17[4] or 18[5] African countries had confirmed resistant parasite populations, and as of 2011[update] that was up to 21.[5] Multiply resistant populations are an increasing problem in the Adamawa Region of Cameroon[6] and south east Mali.[7] The Gibe River Valley in southwest Ethiopia showed universal resistance (in T. congolense isolated from Boran cattle) between July 1989 and February 1993.[8] This likely indicates a permanent loss of function in this area for the tested trypanocides, diminazene aceturate, isometamidium chloride, and homidium chloride.[8]
