Trypanosoma congolense
Protozoan parasite, cause of nagana
From Wikipedia, the free encyclopedia
Trypanosoma congolense is a species of trypanosomes and is the major pathogen responsible for the disease nagana in cattle and other animals including sheep, pigs, goats, horses and camels, dogs,[2] as well as laboratory mice. It is the most common cause of nagana in east Africa, but is also a major cause of nagana in west Africa. This parasite is spread by tsetse flies. In its mammalian host, Trypanosoma congolense only lives in blood vessels, and causes in particular anaemia.[2][3][4][5]
| Trypanosoma congolense | |
|---|---|
Scientific classification  | |
| Domain: | Eukaryota |
| (unranked): | incertae sedis |
| Clade: | Discoba |
| Phylum: | Euglenozoa |
| Class: | Kinetoplastea |
| Order: | Trypanosomatida |
| Family: | Trypanosomatidae |
| Genus: | Trypanosoma |
| Subgenus: | Nannomonas |
| Species: | T. congolense |
| Binomial name | |
| Trypanosoma congolense Broden, 1904 | |
| Synonyms[1] | |
| |
Infection process
T. congolense causes anemia. Nok et al., 2003 find T. congolense to alter the surfaces of erythrocytes which may contribute to this effect.[5]
Drug resistance
Individuals isolated from Boran cattle in the Gibe River Valley in southwest Ethiopia showed universal resistance between July 1989 and February 1993.[6] This likely indicates a permanent loss of function in this area for the tested trypanocides, diminazene aceturate, isometamidium chloride, and homidium chloride.[6]
