Tryptophan tryptophylquinone

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Tryptophan tryptophylquinone
Names
IUPAC name
2-Amino-3-[2-[2-amino-3-(2-carboxyethyl)-6,7-dioxo-1H-indol-4-yl]-1H-indol-3-yl]propanoic acid
Identifiers
3D model (JSmol)
ChemSpider
MeSH Tryptophan+tryptophylquinone
  • InChI=1S/C22H20N4O6/c23-13(22(31)32)7-11-9-3-1-2-4-14(9)25-18(11)12-8-15(27)20(30)19-17(12)10(21(24)26-19)5-6-16(28)29/h1-4,8,13,24-25,27,30H,5-7,23H2,(H,28,29)(H,31,32)
    Key: FBZAAMONQBDWHA-UHFFFAOYSA-N
  • C1=CC=C2C(=C1)C(=C(N2)C3=CC(=O)C(=O)C4=C3C(=C(N4)N)CCC(=O)O)CC(C(=O)O)N
Properties
C22H20N4O6
Molar mass 436.424 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Tryptophan tryptophylquinone (TTQ)[1] is an enzyme cofactor, generated by posttranslational modification of amino acids within the protein. Methylamine dehydrogenase (MADH), an amine dehydrogenase, that requires TTQ for its catalytic function.[2] It is found in the bacteria Paracoccus denitrificans.

References

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