Tulane virus
Species of virus
From Wikipedia, the free encyclopedia
Tulane virus (Recovirus tulani) is a calicivirus isolated from the rhesus monkey.[2] It is the sole member of the Recovirus genus.[3] It is a non-enveloped, positive-sense, single-stranded RNA virus, and its genome, which is approximately 6.7 kilobases in length, is reported shortest among the members of the family Caliciviridae . The genome is organized into three open reading frames (ORFs): ORF1 encodes a nonstructural polyprotein involved in viral replication, ORF2 endcodes the major capsid protein (VP1), and ORF3 encodes a basic minor structural protein (VP2)[4].
| Tulane virus | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Picornavirales |
| Family: | Caliciviridae |
| Genus: | Recovirus |
| Species: | Recovirus tulani |
| Synonyms[1] | |
| |
The virus was first identified in 2008 after being isolated from the stool samples of captive juvenile rhesus macaques (Macaca mulatta) housed at the Tulane National Primate Research Center[4]. It propagates easily in cell lines such as LLC-MK2[5], and recognizes histo-blood group antigens (HBGAs) similar to human noroviruses (HuNoVs)[6]. These features make it a good surrogate candidate for HuNoV studies.
