Type 3c diabetes
Medical condition
From Wikipedia, the free encyclopedia
Type 3c diabetes (also known as pancreatogenic diabetes) is diabetes that comes secondary to pancreatic diseases,[1] involving the endocrine and exocrine (digestive) functions of the pancreas. It also occurs following surgical removal of the pancreas.
| Type 3c diabetes |
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Around 5–10% of cases of diabetes in the Western world are related to pancreatic diseases. Chronic pancreatitis is most often the cause.[1][2]
Presentation
The symptoms of Type 3c diabetes are the same as other forms of diabetes. They include:[citation needed]
- Increased thirst (polydipsia) and dry mouth.
- Frequent urination.
- Fatigue.
- Blurred vision.
- Unexplained weight loss.
- Numbness or tingling in hands or feet.
- Slow-healing sores or cuts.
- Frequent skin and/or vaginal yeast infections.
People with Type 3c diabetes typically also have symptoms of exocrine pancreatic insufficiency, which include:[citation needed]
- Abdominal pain, gas and bloating.
- Constipation.
- Diarrhoea.
- Fatty stools (pale, oily, foul-smelling faeces that float).
- Unexplained weight loss.
The same complications that occur for other types of diabetics (type 1 and type 2) may occur for type 3c diabetics. These include retinopathy, nephropathy, neuropathy, and cardiovascular disease. Patients with this condition are advised to follow the same risk-reduction guidelines as the other diabetics do and keep blood sugars as normal as possible to minimize any complications.[citation needed]
Cause
There are multiple causes. Some of which identified are:
- Pancreatic disease
- Pancreatic resection
- Chronic pancreatitis (caused by exocrine insufficiency, maldigestion, and malnutrition).[3]
- Lacking genes in the E2F group.[4]
Diagnosis
| Diagnostic Criteria for T3cDM |
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Major criteria (all must be fulfilled):
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| Minor Criteria: |
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Management
The condition can be managed by many factors.[citation needed]
Medications
Medications such as insulin may be given in order to lower blood sugars. For not so high blood sugars, oral treatments in the form of a pill or capsule may be given.
Usually, insulin requirements are lower than in type 1 diabetes (SAID).[5] However, therapeutic challenges may arise from the fact that hypoglycaemia is a common complication, owing to the lack of alpha cells.[5]